PICK1-mediated Glutamate Receptor Subunit 2 (GluR2) Trafficking Contributes to Cell Death in Oxygen/Glucose-deprived Hippocampal Neurons

Oxygen and glucose deprivation (OGD) induces delayed cell death in hippocampal CA1 neurons via Ca(2+)/Zn(2+)-permeable, GluR2-lacking AMPA receptors (AMPARs). Following OGD, synaptic AMPAR currents in hippocampal neurons show marked inward rectification and increased sensitivity to channel blockers...

Descripción completa

Detalles Bibliográficos
Autores principales: Dixon, Rebecca M., Mellor, Jack R., Hanley, Jonathan G.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Membrane Transport, Structure, Function, and Biogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682871/
https://www.ncbi.nlm.nih.gov/pubmed/19321442
http://dx.doi.org/10.1074/jbc.M901203200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682871/
https://www.ncbi.nlm.nih.gov/pubmed/19321442
http://dx.doi.org/10.1074/jbc.M901203200

Ejemplares similares