Cargando…

Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers

We have established a systematic high-throughput screen for genes that cause cell death specifically in transformed tumor cells. In a first round of screening cDNAs are detected that induce apoptosis in a transformed human cell line. Positive genes are subsequently tested in a synthetic lethal scree...

Descripción completa

Detalles Bibliográficos
Autores principales: Irshad, Shazia, Mahul-Mellier, Anne-Laure, Kassouf, Nick, Lemarie, Anthony, Grimm, Stefan
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683172/
https://www.ncbi.nlm.nih.gov/pubmed/19282870
http://dx.doi.org/10.1038/cdd.2009.21