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Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers
We have established a systematic high-throughput screen for genes that cause cell death specifically in transformed tumor cells. In a first round of screening cDNAs are detected that induce apoptosis in a transformed human cell line. Positive genes are subsequently tested in a synthetic lethal scree...
Autores principales: | Irshad, Shazia, Mahul-Mellier, Anne-Laure, Kassouf, Nick, Lemarie, Anthony, Grimm, Stefan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683172/ https://www.ncbi.nlm.nih.gov/pubmed/19282870 http://dx.doi.org/10.1038/cdd.2009.21 |
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