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Adaptable gene-specific dye bias correction for two-channel DNA microarrays

DNA microarray technology is a powerful tool for monitoring gene expression or for finding the location of DNA-bound proteins. DNA microarrays can suffer from gene-specific dye bias (GSDB), causing some probes to be affected more by the dye than by the sample. This results in large measurement error...

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Detalles Bibliográficos
Autores principales: Margaritis, Thanasis, Lijnzaad, Philip, van Leenen, Dik, Bouwmeester, Diane, Kemmeren, Patrick, van Hooff, Sander R, Holstege, Frank CP
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683724/
https://www.ncbi.nlm.nih.gov/pubmed/19401678
http://dx.doi.org/10.1038/msb.2009.21