Structure-Function analysis of the CTLA-4 interaction with PP2A

BACKGROUND: CTLA-4 functions primarily as an inhibitor of T cell activation. There are several candidate explanations as to how CTLA-4 modulates T cell responses, but the exact mechanism remains undefined. The tail of CTLA-4 does not have any intrinsic enzymatic activity but is able to associate wit...

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Detalles Bibliográficos
Autores principales: Teft, Wendy A, Chau, Thu A, Madrenas, Joaquín
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683795/
https://www.ncbi.nlm.nih.gov/pubmed/19405949
http://dx.doi.org/10.1186/1471-2172-10-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683795/
https://www.ncbi.nlm.nih.gov/pubmed/19405949
http://dx.doi.org/10.1186/1471-2172-10-23

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