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Structure-Function analysis of the CTLA-4 interaction with PP2A
BACKGROUND: CTLA-4 functions primarily as an inhibitor of T cell activation. There are several candidate explanations as to how CTLA-4 modulates T cell responses, but the exact mechanism remains undefined. The tail of CTLA-4 does not have any intrinsic enzymatic activity but is able to associate wit...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683795/ https://www.ncbi.nlm.nih.gov/pubmed/19405949 http://dx.doi.org/10.1186/1471-2172-10-23 |