Soluble aggregates of the amyloid-β peptide are trapped by serum albumin to enhance amyloid-β activation of endothelial cells

BACKGROUND: Self-assembly of the amyloid-β peptide (Aβ) has been implicated in the pathogenesis of Alzheimer's disease (AD). As a result, synthetic molecules capable of inhibiting Aβ self-assembly could serve as therapeutic agents and endogenous molecules that modulate Aβ self-assembly may infl...

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Detalles Bibliográficos
Autores principales: Reyes Barcelo, Adriana A, Gonzalez-Velasquez, Francisco J, Moss, Melissa A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683804/
https://www.ncbi.nlm.nih.gov/pubmed/19397812
http://dx.doi.org/10.1186/1754-1611-3-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683804/
https://www.ncbi.nlm.nih.gov/pubmed/19397812
http://dx.doi.org/10.1186/1754-1611-3-5

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