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Decytabine enhances cytotoxicity induced by oxaliplatin and 5-fluorouracil in the colorectal cancer cell line Colo-205

BACKGROUND: DNA methylation is an epigenetic phenomenon known to play an important role in the development of cancers, including colorectal cancer (CRC). Aberrant methylation of promoter regions of genes is potentially reversible, and if methylation is important for cancer survival, demethylation sh...

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Detalles Bibliográficos
Autores principales: Flis, Sylwia, Gnyszka, Agnieszka, Misiewicz-Krzemińska, Irena, Spławiński, Jacek
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683807/
https://www.ncbi.nlm.nih.gov/pubmed/19397792
http://dx.doi.org/10.1186/1475-2867-9-10