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Detection and characterization of 3D-signature phosphorylation site motifs and their contribution towards improved phosphorylation site prediction in proteins

BACKGROUND: Phosphorylation of proteins plays a crucial role in the regulation and activation of metabolic and signaling pathways and constitutes an important target for pharmaceutical intervention. Central to the phosphorylation process is the recognition of specific target sites by protein kinases...

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Detalles Bibliográficos
Autores principales: Durek, Pawel, Schudoma, Christian, Weckwerth, Wolfram, Selbig, Joachim, Walther, Dirk
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683816/
https://www.ncbi.nlm.nih.gov/pubmed/19383128
http://dx.doi.org/10.1186/1471-2105-10-117