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Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages

BACKGROUND: Toll-like receptors (TLRs) are present on monocytes and alveolar macrophages that form the first line of defense against inhaled particles. The importance of those cells in the pathophysiology of chronic obstructive pulmonary disease (COPD) has well been documented. Cigarette smoke conta...

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Detalles Bibliográficos
Autores principales: Sarir, Hadi, Mortaz, Esmaeil, Karimi, Khalil, Kraneveld, Aletta D, Rahman, Irfan, Caldenhoven, Eric, Nijkamp, Frans P, Folkerts, Gert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683828/
https://www.ncbi.nlm.nih.gov/pubmed/19409098
http://dx.doi.org/10.1186/1476-9255-6-12