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Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages
BACKGROUND: Toll-like receptors (TLRs) are present on monocytes and alveolar macrophages that form the first line of defense against inhaled particles. The importance of those cells in the pathophysiology of chronic obstructive pulmonary disease (COPD) has well been documented. Cigarette smoke conta...
Autores principales: | Sarir, Hadi, Mortaz, Esmaeil, Karimi, Khalil, Kraneveld, Aletta D, Rahman, Irfan, Caldenhoven, Eric, Nijkamp, Frans P, Folkerts, Gert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683828/ https://www.ncbi.nlm.nih.gov/pubmed/19409098 http://dx.doi.org/10.1186/1476-9255-6-12 |
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