A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the PIK3CA gene

BACKGROUND: Activating mutations in the PIK3CA gene have been identified in a variety of human malignancies and are commonly detected in hotspot codons located in the helical and kinase domains in exons 9 and 20. Existing methodologies for the detection of PIK3CA mutations are time-consuming and/or...

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Detalles Bibliográficos
Autores principales: Hurst, Carolyn D, Zuiverloon, Tahlita CM, Hafner, Christian, Zwarthoff, Ellen C, Knowles, Margaret A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683860/
https://www.ncbi.nlm.nih.gov/pubmed/19402901
http://dx.doi.org/10.1186/1756-0500-2-66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683860/
https://www.ncbi.nlm.nih.gov/pubmed/19402901
http://dx.doi.org/10.1186/1756-0500-2-66

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