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A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the PIK3CA gene
BACKGROUND: Activating mutations in the PIK3CA gene have been identified in a variety of human malignancies and are commonly detected in hotspot codons located in the helical and kinase domains in exons 9 and 20. Existing methodologies for the detection of PIK3CA mutations are time-consuming and/or...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683860/ https://www.ncbi.nlm.nih.gov/pubmed/19402901 http://dx.doi.org/10.1186/1756-0500-2-66 |