The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice

Sindbis virus (SINV), the prototype alphavirus, contains a macro domain in the highly conserved N-terminal region of nonstructural protein 3 (nsP3). However, the biological role of the macro domain is unclear. Mutations of amino acids 10 and 24 from asparagine to alanine in the ADP-ribose binding re...

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Detalles Bibliográficos
Autores principales: Park, Eunhye, Griffin, Diane E.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683903/
https://www.ncbi.nlm.nih.gov/pubmed/19395054
http://dx.doi.org/10.1016/j.virol.2009.03.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683903/
https://www.ncbi.nlm.nih.gov/pubmed/19395054
http://dx.doi.org/10.1016/j.virol.2009.03.031

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