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The nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in mice
Sindbis virus (SINV), the prototype alphavirus, contains a macro domain in the highly conserved N-terminal region of nonstructural protein 3 (nsP3). However, the biological role of the macro domain is unclear. Mutations of amino acids 10 and 24 from asparagine to alanine in the ADP-ribose binding re...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683903/ https://www.ncbi.nlm.nih.gov/pubmed/19395054 http://dx.doi.org/10.1016/j.virol.2009.03.031 |