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Arsenic Activates EGFR Pathway Signaling in the Lung

Arsenic is an established lung carcinogen, however, the carcinogenic mechanisms are currently under investigation. Phosphorylation of the epidermal growth factor receptor (EGFR) has been reported with arsenic exposure in bladder cells. EGFR is a tyrosine kinase transmembrane receptor that regulates...

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Detalles Bibliográficos
Autores principales: Andrew, Angeline S., Mason, Rebecca A., Memoli, Vincent, Duell, Eric J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683921/
https://www.ncbi.nlm.nih.gov/pubmed/19168569
http://dx.doi.org/10.1093/toxsci/kfp015