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How Do Human Cells React to the Absence of Mitochondrial DNA?

BACKGROUND: Mitochondrial biogenesis is under the control of two different genetic systems: the nuclear genome (nDNA) and the mitochondrial genome (mtDNA). The mtDNA is a circular genome of 16.6 kb encoding 13 of the approximately 90 subunits that form the respiratory chain, the remaining ones being...

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Detalles Bibliográficos
Autores principales: Mineri, Rossana, Pavelka, Norman, Fernandez-Vizarra, Erika, Ricciardi-Castagnoli, Paola, Zeviani, Massimo, Tiranti, Valeria
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683933/
https://www.ncbi.nlm.nih.gov/pubmed/19492094
http://dx.doi.org/10.1371/journal.pone.0005713