XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

XBP-1, a transcription factor that drives the unfolded protein response (UPR), is activated in B cells when they differentiate to plasma cells. Here, we show that in the B cells, whose capacity to secrete IgM has been eliminated, XBP-1 is induced normally on induction of differentiation, suggesting...

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Detalles Bibliográficos
Autores principales: Hu, Chih-Chi Andrew, Dougan, Stephanie K, McGehee, Annette M, Love, J Christopher, Ploegh, Hidde L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684024/
https://www.ncbi.nlm.nih.gov/pubmed/19407814
http://dx.doi.org/10.1038/emboj.2009.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684024/
https://www.ncbi.nlm.nih.gov/pubmed/19407814
http://dx.doi.org/10.1038/emboj.2009.117

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