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XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells
XBP-1, a transcription factor that drives the unfolded protein response (UPR), is activated in B cells when they differentiate to plasma cells. Here, we show that in the B cells, whose capacity to secrete IgM has been eliminated, XBP-1 is induced normally on induction of differentiation, suggesting...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684024/ https://www.ncbi.nlm.nih.gov/pubmed/19407814 http://dx.doi.org/10.1038/emboj.2009.117 |