Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets

BACKGROUND: Myostatin (MSTN), a member of the TGF-β superfamily, has been identified as a negative regulator of skeletal muscle mass. Inactivating mutations in the MSTN gene are responsible for the development of a hypermuscular phenotype. In this study, we performed transcriptomic and proteomic ana...

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Detalles Bibliográficos
Autores principales: Chelh, Ilham, Meunier, Bruno, Picard, Brigitte, Reecy, Mark James, Chevalier, Catherine, Hocquette, Jean-François, Cassar-Malek, Isabelle
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684550/
https://www.ncbi.nlm.nih.gov/pubmed/19397818
http://dx.doi.org/10.1186/1471-2164-10-196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684550/
https://www.ncbi.nlm.nih.gov/pubmed/19397818
http://dx.doi.org/10.1186/1471-2164-10-196

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