Dose Escalation Methods in Phase I Cancer Clinical Trials

Phase I clinical trials are an essential step in the development of anticancer drugs. The main goal of these studies is to establish the recommended dose and/or schedule of new drugs or drug combinations for phase II trials. The guiding principle for dose escalation in phase I trials is to avoid exp...

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Detalles Bibliográficos
Autores principales: Le Tourneau, Christophe, Lee, J. Jack, Siu, Lillian L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684552/
https://www.ncbi.nlm.nih.gov/pubmed/19436029
http://dx.doi.org/10.1093/jnci/djp079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684552/
https://www.ncbi.nlm.nih.gov/pubmed/19436029
http://dx.doi.org/10.1093/jnci/djp079

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