Cargando…
Dose Escalation Methods in Phase I Cancer Clinical Trials
Phase I clinical trials are an essential step in the development of anticancer drugs. The main goal of these studies is to establish the recommended dose and/or schedule of new drugs or drug combinations for phase II trials. The guiding principle for dose escalation in phase I trials is to avoid exp...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684552/ https://www.ncbi.nlm.nih.gov/pubmed/19436029 http://dx.doi.org/10.1093/jnci/djp079 |