Ex vivo gene therapy using intravitreal injection of GDNF-secreting mouse embryonic stem cells in a rat model of retinal degeneration

PURPOSE: Safe and prolonged drug delivery to the retina is a key obstacle to overcome in the development of new medicines aimed at treating progressive retinal disease. We took advantage of the ability of embryonic stem cells to survive long-term in foreign tissue and used these cells to deliver neu...

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Detalles Bibliográficos
Autores principales: Gregory-Evans, Kevin, Chang, Francis, Hodges, Matthew D., Gregory-Evans, Cheryl Y.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684563/
https://www.ncbi.nlm.nih.gov/pubmed/19461934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684563/
https://www.ncbi.nlm.nih.gov/pubmed/19461934

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