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Fast Statistical Alignment

We describe a new program for the alignment of multiple biological sequences that is both statistically motivated and fast enough for problem sizes that arise in practice. Our Fast Statistical Alignment program is based on pair hidden Markov models which approximate an insertion/deletion process on...

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Detalles Bibliográficos
Autores principales: Bradley, Robert K., Roberts, Adam, Smoot, Michael, Juvekar, Sudeep, Do, Jaeyoung, Dewey, Colin, Holmes, Ian, Pachter, Lior
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684580/
https://www.ncbi.nlm.nih.gov/pubmed/19478997
http://dx.doi.org/10.1371/journal.pcbi.1000392