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Soluble ST2 Levels Are Associated with Bleeding in Patients with Severe Leptospirosis

BACKGROUND: Severe leptospirosis features bleeding and multi-organ failure, leading to shock and death. Currently it is assumed that both exaggerated inflammation and immune suppression contribute to mortality in sepsis. Indeed, several proinflammatory cytokines are reported to be induced during lep...

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Detalles Bibliográficos
Autores principales: Wagenaar, Jiri F. P., Gasem, M. Hussein, Goris, Marga G. A., Leeflang, Mariska, Hartskeerl, Rudy A., van der Poll, Tom, van 't Veer, Cornelis, van Gorp, Eric C. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684584/
https://www.ncbi.nlm.nih.gov/pubmed/19488407
http://dx.doi.org/10.1371/journal.pntd.0000453