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Abnormalities in Osteoclastogenesis and Decreased Tumorigenesis in Mice Deficient for Ovarian Cancer G Protein-Coupled Receptor 1

Ovarian cancer G protein-coupled receptor 1 (OGR1) has been shown to be a proton sensing receptor in vitro. We have shown that OGR1 functions as a tumor metastasis suppressor gene when it is over-expressed in human prostate cancer cells in vivo. To examine the physiological functions of OGR1, we gen...

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Detalles Bibliográficos
Autores principales: Li, Hui, Wang, Dongmei, Singh, Lisam Shanjukumar, Berk, Michael, Tan, Haiyan, Zhao, Zhenwen, Steinmetz, Rosemary, Kirmani, Kashif, Wei, Gang, Xu, Yan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684630/
https://www.ncbi.nlm.nih.gov/pubmed/19479052
http://dx.doi.org/10.1371/journal.pone.0005705