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Transcriptome-Wide Prediction of miRNA Targets in Human and Mouse Using FASTH

Transcriptional regulation by microRNAs (miRNAs) involves complementary base-pairing at target sites on mRNAs, yielding complex secondary structures. Here we introduce an efficient computational approach and software (FASTH) for genome-scale prediction of miRNA target sites based on minimizing the f...

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Detalles Bibliográficos
Autores principales: Ragan, Chikako, Cloonan, Nicole, Grimmond, Sean M., Zuker, Michael, Ragan, Mark A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684643/
https://www.ncbi.nlm.nih.gov/pubmed/19478946
http://dx.doi.org/10.1371/journal.pone.0005745