Asymmetric Strand Segregation: Epigenetic Costs of Genetic Fidelity?

Asymmetric strand segregation has been proposed as a mechanism to minimize effective mutation rates in epithelial tissues. Under asymmetric strand segregation, the double-stranded molecule that contains the oldest DNA strand is preferentially targeted to the somatic stem cell after each round of DNA...

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Detalles Bibliográficos
Autor principal: Genereux, Diane P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684645/
https://www.ncbi.nlm.nih.gov/pubmed/19503601
http://dx.doi.org/10.1371/journal.pgen.1000509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684645/
https://www.ncbi.nlm.nih.gov/pubmed/19503601
http://dx.doi.org/10.1371/journal.pgen.1000509

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