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Asymmetric Strand Segregation: Epigenetic Costs of Genetic Fidelity?
Asymmetric strand segregation has been proposed as a mechanism to minimize effective mutation rates in epithelial tissues. Under asymmetric strand segregation, the double-stranded molecule that contains the oldest DNA strand is preferentially targeted to the somatic stem cell after each round of DNA...
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684645/ https://www.ncbi.nlm.nih.gov/pubmed/19503601 http://dx.doi.org/10.1371/journal.pgen.1000509 |