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Direct Binding of pRb/E2F-2 to GATA-1 Regulates Maturation and Terminal Cell Division during Erythropoiesis

How cell proliferation subsides as cells terminally differentiate remains largely enigmatic, although this phenomenon is central to the existence of multicellular organisms. Here, we show that GATA-1, the master transcription factor of erythropoiesis, forms a tricomplex with the retinoblastoma prote...

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Detalles Bibliográficos
Autores principales: Kadri, Zahra, Shimizu, Ritsuko, Ohneda, Osamu, Maouche-Chretien, Leila, Gisselbrecht, Sylvie, Yamamoto, Masayuki, Romeo, Paul-Henri, Leboulch, Philippe, Chretien, Stany
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684697/
https://www.ncbi.nlm.nih.gov/pubmed/19513100
http://dx.doi.org/10.1371/journal.pbio.1000123