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Role of regulatory T cells in coronavirus-induced acute encephalitis()

C57BL/6 mice infected with mouse hepatitis virus, strain JHM (JHMV) develop a rapidly fatal acute encephalitis. Previously, we showed that this disease is partially CD4 T cell-mediated since infection with a recombinant JHMV (rJ) mutated in only a single immunodominant CD4 T cell epitope (epitope M1...

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Detalles Bibliográficos
Autores principales: Anghelina, Daniela, Zhao, Jingxian, Trandem, Kathryn, Perlman, Stanley
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684864/
https://www.ncbi.nlm.nih.gov/pubmed/19141357
http://dx.doi.org/10.1016/j.virol.2008.12.014