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A Lipid Receptor Sorts Polyomavirus from the Endolysosome to the Endoplasmic Reticulum to Cause Infection

The mechanisms by which receptors guide intracellular virus transport are poorly characterized. The murine polyomavirus (Py) binds to the lipid receptor ganglioside GD1a and traffics to the endoplasmic reticulum (ER) where it enters the cytosol and then the nucleus to initiate infection. How Py reac...

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Detalles Bibliográficos
Autores principales: Qian, Mengding, Cai, Dawen, Verhey, Kristen J., Tsai, Billy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685006/
https://www.ncbi.nlm.nih.gov/pubmed/19503604
http://dx.doi.org/10.1371/journal.ppat.1000465