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Direct demonstration and quantification of long-range DNA looping by the λ bacteriophage repressor

Recently, it was proposed that DNA looping by the λ repressor (CI protein) strengthens repression of lytic genes during lysogeny and simultaneously ensures efficient switching to lysis. To investigate this hypothesis, tethered particle motion experiments were performed and dynamic CI-mediated loopin...

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Detalles Bibliográficos
Autores principales: Zurla, Chiara, Manzo, Carlo, Dunlap, David, Lewis, Dale E. A., Adhya, Sankar, Finzi, Laura
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685085/
https://www.ncbi.nlm.nih.gov/pubmed/19276206
http://dx.doi.org/10.1093/nar/gkp134