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Bending modes of DNA directly addressed by cryo-electron microscopy of DNA minicircles

We use cryo-electron microscopy (cryo-EM) to study the 3D shapes of 94-bp-long DNA minicircles and address the question of whether cyclization of such short DNA molecules necessitates the formation of sharp, localized kinks in DNA or whether the necessary bending can be redistributed and accomplishe...

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Detalles Bibliográficos
Autores principales: Demurtas, Davide, Amzallag, Arnaud, Rawdon, Eric J., Maddocks, John H., Dubochet, Jacques, Stasiak, Andrzej
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685088/
https://www.ncbi.nlm.nih.gov/pubmed/19282451
http://dx.doi.org/10.1093/nar/gkp137