The proapoptotic dp5 gene is a direct target of the MLK-JNK-c-Jun pathway in sympathetic neurons

The death of sympathetic neurons after nerve growth factor (NGF) withdrawal requires de novo gene expression. Dp5 was one of the first NGF withdrawal-induced genes to be identified and it encodes a proapoptotic BH3-only member of the Bcl-2 family. To study how dp5 transcription is regulated by NGF w...

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Detalles Bibliográficos
Autores principales: Towers, Emily, Gilley, Jonathan, Randall, Rebecca, Hughes, Rosie, Kristiansen, Mark, Ham, Jonathan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685101/
https://www.ncbi.nlm.nih.gov/pubmed/19304750
http://dx.doi.org/10.1093/nar/gkp175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685101/
https://www.ncbi.nlm.nih.gov/pubmed/19304750
http://dx.doi.org/10.1093/nar/gkp175

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