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The proapoptotic dp5 gene is a direct target of the MLK-JNK-c-Jun pathway in sympathetic neurons
The death of sympathetic neurons after nerve growth factor (NGF) withdrawal requires de novo gene expression. Dp5 was one of the first NGF withdrawal-induced genes to be identified and it encodes a proapoptotic BH3-only member of the Bcl-2 family. To study how dp5 transcription is regulated by NGF w...
Autores principales: | Towers, Emily, Gilley, Jonathan, Randall, Rebecca, Hughes, Rosie, Kristiansen, Mark, Ham, Jonathan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685101/ https://www.ncbi.nlm.nih.gov/pubmed/19304750 http://dx.doi.org/10.1093/nar/gkp175 |
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