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Oxidation of a potassium channel causes progressive sensory function loss during ageing

A central question is whether potassium (K(+)) channels, which are key regulators of neuronal excitability, are targets of reactive oxygen species (ROS) and whether these interactions have a role in the mechanisms underlying neurodegeneration. Here, we show that oxidation of K(+) channel KVS-1 durin...

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Detalles Bibliográficos
Autores principales: Cai, Shi-Qing, Sesti, Federico
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685168/
https://www.ncbi.nlm.nih.gov/pubmed/19330004
http://dx.doi.org/10.1038/nn.2291