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Oxidation of a potassium channel causes progressive sensory function loss during ageing
A central question is whether potassium (K(+)) channels, which are key regulators of neuronal excitability, are targets of reactive oxygen species (ROS) and whether these interactions have a role in the mechanisms underlying neurodegeneration. Here, we show that oxidation of K(+) channel KVS-1 durin...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685168/ https://www.ncbi.nlm.nih.gov/pubmed/19330004 http://dx.doi.org/10.1038/nn.2291 |