Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy

BACKGROUND: The COP9/signalosome (CSN) is a highly conserved eight subunit complex that, by deneddylating cullins in cullin-based E3 ubiquitin ligases, regulates protein degradation. Although studied in model human cell lines such as HeLa, very little is known about the role of the CSN in haemopoiet...

Descripción completa

Detalles Bibliográficos
Autores principales: Pearce, Claire, Hayden, Rachel E, Bunce, Christopher M, Khanim, Farhat L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685372/
https://www.ncbi.nlm.nih.gov/pubmed/19400951
http://dx.doi.org/10.1186/1471-2121-10-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685372/
https://www.ncbi.nlm.nih.gov/pubmed/19400951
http://dx.doi.org/10.1186/1471-2121-10-31

Ejemplares similares