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Association between polymorphisms in RMI1, TOP3A, and BLM and risk of cancer, a case-control study

BACKGROUND: Mutations altering BLM function are associated with highly elevated cancer susceptibility (Bloom syndrome). Thus, genetic variants of BLM and proteins that form complexes with BLM, such as TOP3A and RMI1, might affect cancer risk as well. METHODS: In this study we have studied 26 tagged...

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Detalles Bibliográficos
Autores principales: Broberg, Karin, Huynh, Elizabeth, Engström, Karin Schläwicke, Björk, Jonas, Albin, Maria, Ingvar, Christian, Olsson, Håkan, Höglund, Mattias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685436/
https://www.ncbi.nlm.nih.gov/pubmed/19432957
http://dx.doi.org/10.1186/1471-2407-9-140