Cargando…

Transcription factor C/EBPβ isoform ratio regulates osteoclastogenesis through MafB

Disequilibrium between bone-forming osteoblasts and bone-resorbing osteoclasts is central to many bone diseases. Here, we show that dysregulated expression of translationally controlled isoforms of CCAAT/enhancer-binding protein β (C/EBPβ) differentially affect bone mass. Alternative translation ini...

Descripción completa

Detalles Bibliográficos
Autores principales: Smink, Jeske J, Bégay, Valérie, Schoenmaker, Ton, Sterneck, Esta, de Vries, Teun J, Leutz, Achim
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685610/
https://www.ncbi.nlm.nih.gov/pubmed/19440205
http://dx.doi.org/10.1038/emboj.2009.127