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Transcription factor C/EBPβ isoform ratio regulates osteoclastogenesis through MafB
Disequilibrium between bone-forming osteoblasts and bone-resorbing osteoclasts is central to many bone diseases. Here, we show that dysregulated expression of translationally controlled isoforms of CCAAT/enhancer-binding protein β (C/EBPβ) differentially affect bone mass. Alternative translation ini...
Autores principales: | Smink, Jeske J, Bégay, Valérie, Schoenmaker, Ton, Sterneck, Esta, de Vries, Teun J, Leutz, Achim |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685610/ https://www.ncbi.nlm.nih.gov/pubmed/19440205 http://dx.doi.org/10.1038/emboj.2009.127 |
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