Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria

Visceral adiposity in obesity causes excessive free fatty acid (FFA) flux into the liver via the portal vein and may cause fatty liver disease and hepatic insulin resistance. However, because animal models of insulin resistance induced by lipid infusion or a high fat diet are complex and may be acco...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Seiji, Takamura, Toshinari, Matsuzawa-Nagata, Naoto, Takayama, Hiroaki, Misu, Hirofumi, Noda, Hiroyo, Nabemoto, Satoko, Kurita, Seiichiro, Ota, Tsuguhito, Ando, Hitoshi, Miyamoto, Ken-ichi, Kaneko, Shuichi
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685662/
https://www.ncbi.nlm.nih.gov/pubmed/19332540
http://dx.doi.org/10.1074/jbc.M901488200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685662/
https://www.ncbi.nlm.nih.gov/pubmed/19332540
http://dx.doi.org/10.1074/jbc.M901488200

Ejemplares similares