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The limits of testing particle-mediated oxidative stress in vitro in predicting diverse pathologies; relevance for testing of nanoparticles

In vitro studies with particles are a major staple of particle toxicology, generally used to investigate mechanisms and better understand the molecular events underlying cellular effects. However, there is ethical and financial pressure in nanotoxicology, the new sub-specialty of particle toxicology...

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Detalles Bibliográficos
Autores principales: Donaldson, Ken, Borm, Paul JA, Castranova, Vincent, Gulumian, Mary
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685764/
https://www.ncbi.nlm.nih.gov/pubmed/19397808
http://dx.doi.org/10.1186/1743-8977-6-13