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The limits of testing particle-mediated oxidative stress in vitro in predicting diverse pathologies; relevance for testing of nanoparticles
In vitro studies with particles are a major staple of particle toxicology, generally used to investigate mechanisms and better understand the molecular events underlying cellular effects. However, there is ethical and financial pressure in nanotoxicology, the new sub-specialty of particle toxicology...
Autores principales: | Donaldson, Ken, Borm, Paul JA, Castranova, Vincent, Gulumian, Mary |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685764/ https://www.ncbi.nlm.nih.gov/pubmed/19397808 http://dx.doi.org/10.1186/1743-8977-6-13 |
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