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Daptomycin in experimental murine pneumococcal meningitis

BACKGROUND: Daptomycin, a lipopeptide antibiotic, could be an alternative to vancomycin for treatment of pneumococcal meningitis. We determined the activity of daptomycin versus vancomycin, with dexamethasone as an adjuvant, in a murine model of pneumococcal meningitis. METHODS: Ninety-six 25–30 gra...

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Detalles Bibliográficos
Autores principales: Mook-Kanamori, Barry B, Rouse, Mark S, Kang, Cheol-In, van de Beek, Diederik, Steckelberg, James M, Patel, Robin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685802/
https://www.ncbi.nlm.nih.gov/pubmed/19405978
http://dx.doi.org/10.1186/1471-2334-9-50