Competitive Inhibition of Thyroidal Uptake of Dietary Iodide by Perchlorate Does Not Describe Perturbations in Rat Serum Total T(4) and TSH

BACKGROUND: Perchlorate (ClO(4)(−)) is an environmental contaminant known to disrupt the thyroid axis of many terrestrial and aquatic species. ClO(4)(−) competitively inhibits iodide uptake into the thyroid at the sodium/iodide symporter and disrupts hypothalamic–pituitary–thyroid (HPT) axis homeost...

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Detalles Bibliográficos
Autores principales: McLanahan, Eva D., Andersen, Melvin E., Campbell, Jerry L., Fisher, Jeffrey W.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685834/
https://www.ncbi.nlm.nih.gov/pubmed/19479014
http://dx.doi.org/10.1289/ehp.0800111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685834/
https://www.ncbi.nlm.nih.gov/pubmed/19479014
http://dx.doi.org/10.1289/ehp.0800111

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