The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes

Elevations of the levels of N-acetyl-aspartyl-glutamate (NAAG) and N-acetyl-aspartate (NAA) are associated with myelin loss in the leucodystrophies Canavan's disease and Pelizaeus-Merzbacher-like disease. NAAG and NAA can activate and antagonize neuronal N-methyl-D-aspartate (NMDA) receptors, a...

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Detalles Bibliográficos
Autores principales: Kołodziejczyk, Karolina, Hamilton, Nicola B., Wade, Anna, Káradóttir, Ragnhildur, Attwell, David
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685922/
https://www.ncbi.nlm.nih.gov/pubmed/19383832
http://dx.doi.org/10.1093/brain/awp087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685922/
https://www.ncbi.nlm.nih.gov/pubmed/19383832
http://dx.doi.org/10.1093/brain/awp087

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