A Liposome-Based Mycobacterial Vaccine Induces Potent Adult and Neonatal Multifunctional T Cells through the Exquisite Targeting of Dendritic Cells

BACKGROUND: In the search for more potent and safer tuberculosis vaccines, CAF01 was identified as a remarkable formulation. Based on cationic liposomes and including a synthetic mycobacterial glycolipid as TLR-independent immunomodulator, it induces strong and protective T helper-1 and T helper-17...

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Detalles Bibliográficos
Autores principales: Kamath, Arun T., Rochat, Anne-Françoise, Christensen, Dennis, Agger, Else Marie, Andersen, Peter, Lambert, Paul-Henri, Siegrist, Claire-Anne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685976/
https://www.ncbi.nlm.nih.gov/pubmed/19492047
http://dx.doi.org/10.1371/journal.pone.0005771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685976/
https://www.ncbi.nlm.nih.gov/pubmed/19492047
http://dx.doi.org/10.1371/journal.pone.0005771

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