Mosquitoes Put the Brake on Arbovirus Evolution: Experimental Evolution Reveals Slower Mutation Accumulation in Mosquito Than Vertebrate Cells

Like other arthropod-borne viruses (arboviruses), mosquito-borne dengue virus (DENV) is maintained in an alternating cycle of replication in arthropod and vertebrate hosts. The trade-off hypothesis suggests that this alternation constrains DENV evolution because a fitness increase in one host usuall...

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Detalles Bibliográficos
Autores principales: Vasilakis, Nikos, Deardorff, Eleanor R., Kenney, Joan L., Rossi, Shannan L., Hanley, Kathryn A., Weaver, Scott C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685980/
https://www.ncbi.nlm.nih.gov/pubmed/19503824
http://dx.doi.org/10.1371/journal.ppat.1000467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685980/
https://www.ncbi.nlm.nih.gov/pubmed/19503824
http://dx.doi.org/10.1371/journal.ppat.1000467

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