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Interfering with Wnt signalling alters the periodicity of the segmentation clock

Somites are embryonic precursors of the ribs, vertebrae and certain dermis tissue. Somite formation is a periodic process regulated by a molecular clock which drives cyclic expression of a number of clock genes in the presomitic mesoderm. To date the mechanism regulating the period of clock gene osc...

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Detalles Bibliográficos
Autores principales: Gibb, Sarah, Zagorska, Anna, Melton, Kristin, Tenin, Gennady, Vacca, Irene, Trainor, Paul, Maroto, Miguel, Dale, J. Kim
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686089/
https://www.ncbi.nlm.nih.gov/pubmed/19272372
http://dx.doi.org/10.1016/j.ydbio.2009.02.035